Mitral endocarditis caused by Achromobacter xylosoxidans in an older patient: Case report and literature review

Mitral endocarditis caused by Achromobacter xylosoxidans in an older patient: Case report and literature review

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We report a Hockey Protective - Starter Kits rare case of recurrent Achromobacter xylosoxidans bacteremia in an older woman in 2014 and 2020.During the more recent bacteremia, a diagnosis of mitral endocarditis was made.The patient could not have surgery because of severe comorbidities and a high operative risk.Combined antibiotic therapy was given with piperacillin/tazobactam and trimethoprim/sulfamethoxazole (TMP/SMX).Antibiotic therapy was administered for six weeks with a good response, but the patient relapsed after six days with A.

xylosoxidans bacteremia and cardiac decompensation.Antibiotic therapy was resumed, using meropenem and UHF TMP/SMX, but the patient died one month after the recurrence.We review the 22 cases of A.xylosoxidans endocarditis that have been described in the literature.